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KMID : 1161519990030030269
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Animal Cells and Systems
1999 Volume.3 No. 3 p.269 ~ p.273
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Changes of the somatostatin?immunoreactive cells in the pancreas of the Korean native goat (capra hircus) during development
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Ku Sae-Kwang
Park Ki-Dae
Lee Hyeung-Sik
Lee Jae-Hyun
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Abstract
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The distribution and relative frequency of somatostatin?immunoreactive cells in the pancreas were studied during developmental stages (fetus, neonate, 1?month?old, 6?month?otd and adult) of the Korean native goat by immuno?histochemical methods. Somatostatin?immunoreactive cells were detected in the exocrine of all ages, in the endocrine portions (pancreatic islets) from the neonate, and in the pancreatic duct of the 1?month?old. The relative frequencies of these cells in the pancreatic islets increased with age. However, there were no age?related changes in the relative frequencies of somatostatin?immunoreactive cells in the exocrine and pancreatic duct. Generally, they were distributed in the interacinar spaces, the epithelium of the pancreatic duct, or dispersed in the peripheral zone of the pancreatic islets in all ages. However, clusters consisting of 3?4 cells were also found in the subepithelial connective tissues from the 1?month?old. In addition, the distributions in the endocrine portions of the adult were divided into two patterns: 1) they are dispersed in the marginal regions with moderate or low frequencies, or 2) in the inner zone with high frequencies.
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KEYWORD
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Developing pancreas, Immunohistochemistry, Korean native goat, Somatostatin-immunoreactive cell
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